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ศาสตราจารย์ดร.ภญ. วราภรณ์ จรรยาประเสริฐ

ศาสตราจารย์ดร.ภญ. วราภรณ์ จรรยาประเสริฐ

varaporn.jun@mahidol.ac.th

varaporn.jun@mahidol.ac.th
อาจารย์ประจำภาควิชาเภสัชกรรม

ผลงานวิจัยตีพิมพ์

2021

  1. Effect of chemical linkers of curcumin conjugated hyaluronic acid on nanoparticle properties and in vitro performances in various cancer cells
    Thummarati P, Suksiriworapong J, Sakchaisri K, Junyaprasert VB*. Journal of drug delivery science and technology 2021; 61: 102323.


2020

  1. Antibacterial oral sprays from kaffir lime (Citrus hystrix DC.) fruit peel oil and leaf oil and their activities against respiratory tract pathogens
    Srifuengfung S, Bunyapraphatsara N, Satitpatipan V, Tribuddharat C, Junyaprasert VB, Tungrugsasut W, Srisukh V*. Journal of traditional and complementary medicine 2020; 10(6): 594-598.

  2. Effect of lipid and oil compositions on physicochemical properties and photoprotection of octyl methoxycinnamate-loaded nanostructured lipid carriers (NLC)
    Teeranachaideekul V*, Morakul B, Boonme P, Pornputtapitak W, Junyaprasert V. Journal of oleo science 2020; 69(12): 1627-1639.

  3. Proniosomes: An effective carrier for dermal and transdermal delivery
    Morakul B*, Junyaprasert VB. Songklanakarin journal of science and technology 2020; 42(6): 1171-1186.


2019

  1. Impact of uncharged and charged stabilizers on in vitro drug performances of clarithromycin nanocrystals
    Soisuwan S, Teeranachaideekul V, Wongrakpanich A, Langguth P, Junyaprasert VB*. European Journal of Pharmaceutics and Biopharmaceutics 2019; 137: 68-76.

  2. Niosomal delivery of pumpkin seed oil: development, characterisation, and physical stability
    Morakul B*, Teeranachaideekul V, Buraphacheep Junyaprasert V. Journal of Microencapsulation -


2018

  1. Fabrication and evaluation of Eudragit® polymeric films for transdermal delivery of piroxicam
    Chantasart D*, Tocanitchart P, Wongrakpanich A, Teeranachaideekul V, Junyaprasert VB. Pharmaceutical Development and Technology 2018; (Article in Press)

  2. In vitro performances and cellular uptake of clarithromycin nanocrystals produced by media milling technique
    Soisuwan S., Teeranachaideekul V., Wongrakpanich A., Langguth P., Junyaprasert V.B. Powder Technology 2018; 338: 471-480.

  3. Synthesis and properties of a biodegradable polymer-drug conjugate: methotrexate-poly(glycerol adipate)
    Suksiriworapong J*, Taresco V, Ivanov DP, Styliari ID, Sakchaisri K, Junyaprasert VB, Garnett MC. Colloids and Surfaces B: Biointerfaces 2018; 167: 115-125

  4. Vegetable oil-based nanoemulsions containing curcuminoids: Formation optimization by phase inversion temperature method
    Jintapattanakit A*, Hasan HM, Junyaprasert VB. Journal of Drug Delivery Science and Technology 2018; 44: 289-297


2017

  1. Effect of binary solid lipid matrix of wax and triglyceride on lipid crystallinity, drug-lipid interaction and drug release of ibuprofen-loaded solid lipid nanoparticles (SLN) for dermal delivery
    Chantaburanan T, Teeranachaideekul V, Chantasart D, Jintapattanakit A, Junyaprasert VB*. Journal of Colloid and Interface Science 2017; 504: 247-256

  2. Effect of Curcuma comosa extracts on the functions of peptide transporter and P-glycoprotein in intestinal epithelial cells.
    Kawami M*, Yamada Y, Toshimori F, Issarachot O, Junyaprasert VB, Yumoto R, Takano M. Pharmazie 2017; 72: 123-127

  3. Influence of state and crystallinity of lipid matrix on physicochemical properties and permeation of capsaicin-loaded lipid nanoparticles for topical delivery
    Teeranachaideekul V, Chantaburanan T, Junyaprasert VB*. Journal of Drug Delivery Science and Technology 2017; 39: 300-307.

  4. Investigation of cationized triblock and diblock poly(ε-caprolactone)-co-poly(ethylene glycol) copolymers for oral delivery of enoxaparin: In vitro approach
    Charoongchit P, Suksiriworapong J, Mao S, Sapin-Minet A, Maincent P, Junyaprasert VB*. Acta Biomaterialia 2017; 61: 180-192

  5. Nanocrystals for enhancement of oral bioavailability of poorly water-soluble drugs
    Junyaprasert VB*, Morakul B. Asian Journal of Pharmaceutical Sciences 2017; 10 (1): 13-23.

  6. Self-aggregation of cationically modified poly(ε-caprolactone)2-co-poly(ethylene glycol) copolymers: Effect of cationic grafting ligand and poly(ε-caprolactone) chain length
    Charoongchit P, Suksiriworapong J, Sripha K, Mao S, Sapin-Minet A, Maincent P, Junyaprasert VB*. Materials Science and Engineering C 2017; 72: 444-455


2016

  1. Comparison of poly(ε-caprolactone) chain lengths of poly(ε-caprolactone)-co-d-α-tocopheryl-poly(ethylene glycol) 1000 succinate nanoparticles for enhancement of quercetin delivery to SKBR3 breast cancer cells.
    Suksiriworapong J*, Phoca K, Ngamsom S, Sripha K, Moongkarndi P, Junyaprasert VB. European Journal of Pharmaceutics and Biopharmaceutics. 2016; 101: 15–24.


2015

  1. Effect of hydrophobic nanoparticle cores on the characteristics of poly(ε-caprolactone)-co-d-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles loaded with camptothecin
    Sirithananchai Y, Junyaprasert VB, Sakchaisri K, Suksiriworapong J*. Mahidol University Journal of Pharmaceutical Sciences 2015; 42 (4), 169-177

  2. Enhanced toxicity and cellular uptake of methotrexate-conjugated nanoparticles in folate receptor-positive cancer cells by decorating with folic acid-conjugated d-α-tocopheryl polyethylene glycol 1000 succinate
    Junyaprasert VB*, Dhanahiranpruk S, Suksiriworapong J, Sripha K, Moongkarndi P. Colloids and Surfaces B: Biointerfaces 2015; 136: 383-393

  3. Nanocrystals for enhancement of oral bioavailability of poorly water-soluble drugs
    Junyaprasert VB*, Morakul B. Asian Journal of Pharmaceutical Sciences 2015; 10(1): 13-23.


2014

  1. Development and characterization of lyophilized diazepam-loaded polymeric micelles.
    Suksiriworapong J*, Rungvimolsin T, A-gomol A, Junyaprasert VB, Chantasart D. AAPS PharmSciTech 2014; 15(1): 52-64

  2. Development of SEDDS/SMEDDS of sweet basil oil and fingerroot oil for using in drinking water for chickens
    Boonme P, Junyaprasert VB*. Thai Journal of Veterinary Medicine 2014; 44(3): 297-305

  3. Dissolution enhancement and in vitro performance of clarithromycin nanocrystals produced by precipitation-lyophilization-homogenization method.
    Morakul B*, Suksiriworapong J, Chomnawang MT, Langguth P, Junyaprasert VB. European Journal of Pharmaceutics and Biopharmaceutics 2014; 88(3): 886-896

  4. Folic acid-modified methotrexate-conjugated PEGylated poly(ε-caprolactone) nanoparticles for targeted delivery
    Issarachot O, Suksiriworapong J, Takano M, Yumoto R, Junyaprasert VB*. Journal of Nanoparticle Research 2014; 16(2): 1-15

  5. In vitro and in vivo evaluation of chitosan graft glyceryl monooleate as peroral delivery carrier of enoxaparin
    Wang L, Li L, Sun Y, Ding J, Li J, Duan X, Li Y, Junyaprasert VB, Mao S*. International Journal of Pharmaceutics 2014; 471(1-2): 391-399


2013

  1. Exploration of hydrophobic modification degree of chitosan-based nanocomplexes on the oral delivery of enoxaparin
    Wang L, Li L, Sun Y, Tian Y, Li Y, Li C, Junyaprasert VB, Mao S*. European Journal of Pharmaceutical Sciences 2013; 50(3เม.ย.): 263-271

  2. Influence of chemical penetration enhancers on skin permeability of ellagic acid-loaded niosomes
    Junyaprasert VB*, Singhsa P, Jintapattanakit A Asian Journal of Pharmaceutical Sciences 2013; 8(2): 110-117

  3. Modification of tricomponent and dicomponent poly(ε-caprolactone)-co- poly(ethylene glycol) with methotrexate and folic acid
    Issarachot O, Suksiriworapong J, Sripha K, Junyaprasert VB*. Journal of Applied Polymer Science 2013; 129(2): 721-734

  4. Precipitation-lyophilization-homogenization (PLH) for preparation of clarithromycin nanocrystals: Influencing factors on physicochemical properties and stability
    Morakul B, Suksiriworapong J, Leanpolchareanchai J, Junyaprasert VB*. International Journal of Pharmaceutics 2013; 457(1): 187-196


2012

  1. Functionalized (poly(ฮต-caprolactone)) 2-poly(ethylene glycol) nanoparticles with grafting nicotinic acid as drug carriers
    Suksiriworapong J, Sripha K, Kreuter J, Junyaprasert VB*. International Journal of Pharmaceutics 2012; 423(2): 562-570

  2. In vitro antifungal activities of longan (Dimocarpus longan Lour.) seed extract
    Rangkadilok N, Tongchusak S, Boonhok R, Chaiyaroj SC, Junyaprasert VB, Buajeeb W, Akanimanee J, Raksasuk T, Suddhasthira T, Satayavivad J*. Fitoterapia 2012; 83(3): 545-553

  3. Physicochemical properties and skin permeation of Span 60/Tween 60 niosomes of ellagic acid
    Junyaprasert VB*, Singhsa P, Suksiriworapong J, Chantasart D. International Journal of Pharmaceutics 2012; 423(2): 303-311


2011

  1. Investigation of Polymer and Nanoparticle Properties with Nicotinic Acid and p-Aminobenzoic Acid Grafted on Poly(epsilon-caprolactone)-Poly(ethylene glycol)-Poly(epsilon-caprolactone) via Click Chemistry
    Suksiriworapong J, Sripha K, Kreuter J, Junyaprasert VB*. Bioconjugate Chem 2011; 22(4): 582-594

  2. Lipid-Based Nanocarriers for Cutaneous Administration of Pharmaceutics
    Souto EB, Teeranachaideekul V, Boonme P, Muller RH, Junyaprasert VB. Encyclopedia of Nanoscience and Nanotechnology 2011; 15: 479-491


2010

  1. Bioadhesion and oral absorption of enoxaparin nanocomplexes.
    Sun W, Mao S*, Wang Y, Junyaprasert VB, Zhang T, Na L, Wang J. Int J Pharm 2010; 386(2): 275-281.

  2. Comparative study of ibuprofen and indomethacin loaded poly(caprolactone) nanoparticle: Physicochemical properties
    Suksiriworaponga J, Sripha K, Kreuterc J, Junyaprasert VB*. Mahidol J Pharm. Sci 2010; 37(1-2): 17-27.

  3. Effect of Thai plant extracts on P-glycoprotein function and viability in paclitaxel-resistant hepG2 cells.
    Kawami M, Yumoto R, Nagai J, Junyaprasert VB, Soonthornchareonnon N, Patanasethanont D, Sripanidkulchai BO, Takano M*. Drug Metabo Pharmacok 2010; 25(2): 155-162.

  4. Nasal absorption and local tissue reaction of insulin nanocomplexes of trimethyl chitosan derivatives in rats
    Jintapattanakit A, Peungvicha P, Sailasuta A, Kissel T, Junyaprasert VB*. J Pharm Pharmacol 2010; 62(5):583-591.

  5. Synthesis and characterization of bioactive molecules grafted on poly (ɛ-caprolactone) by "click" chemistry.
    Suksiriworapong J, Sripha K*, Junyaprasert VB. Polymer 2010; 51(11): 2286-2295.


2009

  1. Applicable “Click Chemistry” on Conjugation of Ibuprofen and Indomethacin on Poly(eCL) and Poly (eCL)-co-Peg-co-Poly (eCL)
    Roopyai K, Changpoon P, Suksiriworapong J, Junyaprasert VB, Sripha K*. Thai J Pharm Sci. 2009; 33(Suppl.)

  2. Effect of lipid types on physicochemical characteristics, stability and antioxidant activity of gamma-oryzanol-loaded lipid nanoparticles
    Sakulkhu U*, Bejrapha P, Opanasopit P, Bunyapraphatsara N, Junyaprasert V, Puttipipatkhachorn S, Ruktanonchai U. J Microencapsul 2009; 26(7): 614-626.

  3. Microemulsions and nanoemulsions: Novel vehicles for whitening cosmeceuticals
    Boonme P*, Junyaprasert VB, Suksawad N, Songkro S. J Biomed Nanotech 2009; 5(4): 373-383.

  4. Physicochemical characteristics, cytotoxicity, and antioxidant activity of three lipid nanoparticulate formulations of alpha-lipoic acid
    Ruktanonchai U*, Bejrapha P, Sakulkhu U, Opanasopit P, Bunyapraphatsara N, Junyaprasert VB, Puttipipatkhachorn S. AAPS Pharm Sci Tech 2009; 10(1): 227-234.

  5. Q10-loaded NLC versus nanoemulsions: Stability, rheology and in vitro skin permeation
    Junyaprasert VB*, Teeranachaideekul V, Souto EB, Boonme P, Müller RH. Int J Pharm 2009; 37(1-2): 207-214.

  6. The role of mucoadhesion of trimethyl chitosan and pygylated trimethyl chitosan and pegylated trimethyl chitosan nanocomplexes in insulin uptake
    Jintapatanakit A, Junyaprasert VB*, Kissel T. Journal of Pharmaceutical Sciences 2009; 98(12): 4818-4830.


2008

  1. Aerosol OT microemulsions as carriers for transdermal delivery of hydrophobic and hydrophilic local anesthetics
    Junyaprasert VB, Boonme P, Wurster D.E, Rades T. Drug Deliv 2008; 15(5): 323-330 June

  2. Development of ascorbyl palmitate nanocrystals applying the nanosuspension technology
    Teeranachaideekul V, Junyaprasert VB, Souto EB, Muller RH Int J Pharm 2008; 354(1-2): 227-234. Apr

  3. Effect of Charged and Non-ionic Membrane Additives on Physicochemical Properties and Stability of Niosomes
    Junyaprasert VB, Teeranachaideekul V, Supaperm T. AAPS Pharm Sci Tech 2008; 9(3):851-859

  4. Effect of tripolyphosphate on physical and enzymatic stabilities of insulin loaded nanoparticles of N-trimethyl chitosa
    Jintapattanakit A, Kissel T, Junyaprasert VB. Frontiers in Plant Science 2008; 35(1-4): 1-7

  5. Floating properties and release characteristics of hollow microspheres of acyclovir
    Junyaprasert VB*, Pornsuwannapha S. Drug Deliv 2008; 15(5): 331-341. June

  6. Influence of oil content on physicochemical properties and skin distribution of Nile red-loaded NLC 
    Teeranachaideekul V, Boonme P, Souto EB, Muller RH, Junyaprasert VB*. J Control Release 2008; 128(2): 134-141. Jun

  7. Physicochemical characterization and in vitro release studies of ascorbyl palmitate-loaded semi-solid nanostructured lipid carriers (NLC gels)
    Teeranachaideekul V, Souto EB, Müller RH, Junyaprasert VB*. J Microencapsul 2008; 25(2): 111-120. Mar

  8. Physicochemical properties and biocompatibility of N-trimethyl chitosan: Effect of quaternization and dimethylation
    Jintapattanakit A, Mao S, Kissel T, Junyaprasert VB*. Eur J Pharm Biopharm 2008; 70(2): 563-571

  9. Release profile comparison and stability of diltiazem-resin microcapsules in sustauned release suspensions.
    Junyaprasert VB*, Manwiwattanakul G. Int J Pharm 2008; 352(1-2): 81-91. Mar

  10. The effect of cetyl palmitate crystallinity on physical properties of gamma-oryzanol encapsulated in solid lipid nanoparticles
    Ruktanonchai U*, Limpakdee S, Meejoo S, Sakulkhu U, Bunyapraphatsara N, Junyaprasert VB, Puttipipatkhachorn S. Nanotechnology. 2008; 19(9): art.no.095701. Feb


2007

  1. Cetyl palmitate-based NLC for topical delivery of coenzyme Q10 - development, physicochemical characterization and in vitro release studies
    Teeranachaideekul V, Souto EB, Junyaprasert VB, Muller RH. Eur J Pharm Biopharm 2007; 67(1) : 141-148, Aug.

  2. Encapsulation of ascorbyl palmitate in nanostructures lipid carriers (NLC) – Effects of formulation parameters on physicochemical stability
    Teeranachaideekul V, Muller RH, Junyaprasert VB*. Int J Pharm 2007; 340(1-2) Aug: 198-206

  3. Enhancement of the skin permeation of clindamycin phosphate by aerosol OT/1-butanol microemulsions.
    Junyaprasert VB*, Leatwimonlak S, Boonme P, Boonsaner P. Drug Dev Ind Pharm 2007; 33(8) Aug:874-880

  4. Peroral delivery of insulin using chitosan derivatives: A comparative study of polyelectrolyte nanocomplexes and nanoparticles
    Jintapatanakit A, Junyaprasert VB, Mao S, Bakowsky U, Kissel T*. Int J Pharm 2007; 342(1-2) Sep: 240-249.

  5. Transdermal delivery of hydrophobic and hydrophilic local anthesthetics from o/w and w/o Brij 97-based microemulsions
    Junyaprasert VB*, Boonme P, Songkro S, Krauel K, Rades T. J Pharm Pharmceut Sci 2007; 10(3): 288-298


2006

  1. Characterization of microstructures formed in isopropyl palmitate/water/Aerosol OT:1-butanol (2:1) system
    Boonme P*, Krauel K, Graf A, Rades T, Junyaprasert VB. Pharmazie 2006; 61: 927-932

  2. Influence of drug-polymer interaction on release characteristics of diltiazem HCl matrix tablets.
    Sarisuta N, Pattanasriroj P, Lawanprasert P, Junyaprasert VB. Proceedings of the 5th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Tec 2006. Geneva, Switzerland: March 2006. 2006

  3. Inhibitory effect of Thai plant extracts on p-glycoprotein mediated efflux
    Junyaprasert VB*, Soonthornchareonnon N, Thongpraditchote S, Murakami T, Takano M. Phytother Res 2006; 20: 79-81


2005

  1. Gel preparation development from Derris reticulata Craib. Extract as an anti-herpes simplex drug.
    Wisetsutthichai S, Techamahamaneerat S, Junyaprasert V, Soonthornchareonnon N. Thai J Phytopharmacy 2005; 12(2): 11-22.


2004

  1. Application of hot-melt coating for controlled release of propranolol hydrochloride pellets.
    Sinchaipanid N*, Junyaprasert V, Mitrevej A. Powder Tech 2004;141(3): 203-209.

  2. Effects of polyhydroxy compounds on the formation of microemulsions of isopropyl myristate, water and Brij® 97
    Boonme P, Songkro S, Junyaprasert VB Mahidol J Pharm Sci 2004, 31(1-2), 8-13


2002

  1. Study of fluocinolone acetonide release from various gelling agents
    Junyaprasert VB, Peungchana N, Pensawang P Thai J Hosp Pharm 2002; 12(3): 208-216


2001

  1. Effect of process variables on the microencapsulation of vitamin A palmitate by gelatin-acacia coacervation
    Junyaprasert VB*, Mitrevej A, Sinchaipanid N, Boonme P, Wurster DE Drug Dev Ind Pharm 2001; 27(6): 561-566


2000

  1. Development and comparative stability of antihistamine drops
    Junyaprasert VB, Sinchaipanid N, Modmolthin P, Ubonpithak F Thai J Hosp Pharm 2000; 9(3): 256-263

  2. Stability of nearly saturate lidocaine hydrochloride solutions
    Junyaprasert VB, Kraivaphan P, Suthumwaraporn W Mahidol J Pharm Sci 2000; 27(1-4): 14-18


1999

  1. Effects of a herbal sodium bicarbonate dentrifice on plaque and gingivitis : a six month clinical study.
    Chithumnong P, Kraivaphan P, Triratana T, Amornchat C, Junyaprasert V Mahidol Dent J 1999; 19 (1-3):43-9

  2. The antibacterial properties of herbal toothpaste : an in vitro and in vivo study.
    Amonchat C, Junyaprasert V J Health Science 1999 ; 8 (2) : 202-9


1998

  1. Direct compression properties of spray dried modified tapioca starch.
    Mitrevej A, Sinchaipanid N, Junyaprasert V Proceeding of 1st European Symposium Process Technology in Pharmaceutical and Nutritional Sciences Nurnberg, Germany, 1998; 216-26


1996

  1. Effect of grinding of b-cyclodextrin and glybenclamide on tablet properties. Part I. In Vitro.
    Mitrevej A, Sinchaipanid N, Junyaprasert V Drug Dev Ind Pharm 1996; 22 (1): 120-130


1994

  1. Effect of microcrystalline cellulose on compaction and disintegration of direct compression fillers.
    Sinchaipanid N, Mitrevej A, Junyaprasert V Proceeding of the 15th Asian Congress of Pharmaceutical Sciences Bangkok, Thailand, 1994; 15:263-68

  2. Preparation of fast release indomethacin capsule.
    Mitrevej A. Sinchaipanid N, Junyaprasert V Mahidol J Pharm Sci 1994; 21(4): 133-42

  3. The use of Fouier transform infrared (FT-IR) spectroscopy to determine the diffusion coefficients of alcohols in polydimethylsiloxane.
    Buraphacheep V, Wurster DE, Wurster DE. Pharm Res 1994; 11(4):561-5


1993

  1. The determination of diffusion coefficients in semisolids by Fourier transform (FT-IR) spectroscopy.
    Wurster DE, Buraphacheep V, Patel JM. Pharm Res 1993;10:616-9



หมายเหตุ: ชื่อที่ใช้ในการทำวิจัยของ ศาสตราจารย์ดร.ภญ. วราภรณ์ จรรยาประเสริฐ ได้แก่ วราภรณ์ จรรยาประเสริฐ ; วราภรณ์ บูรพาชีพ ; Junyaprasert V ; Buraphacheep V ; Junyaprasert VB ; Buraphacheep VB ;

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