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Eng |
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รศ.ดร.ภญ. มัลลิกา ชมนาวังรศ.ดร.ภญ. มัลลิกา ชมนาวังmullika.tra@mahidol.ac.thmullika.tra@mahidol.ac.thอาจารย์ประจำภาควิชาจุลชีววิทยา |
ข้อมูลส่วนตัว |
As declared by the World Health Organization (WHO), antimicrobial resistance (AMR) is one of the top ten global public health threats facing humanity in the coming decade. Importantly, there is a growing global concern about the rapid increase of AMR while the development of new antimicrobials is on steady decline. Therefore, the aim of our research group is to highlight new advances in understanding of antimicrobial resistance mechanisms at the molecular level as well as the epidemiology and distribution of antimicrobial resistance patterns. The long-term goal of the lab is to develop novel diagnostics and treatment options including antimicrobials using advance technology.
SELECTED PUBLICATIONS:
1. Khuntayaporn P, Thirapanmethee K, Chomnawang MT. An update of mobile colistin resistance in non-fermentative Gram-negative bacilli. Front Cell Infect Microbiol. 2022. 12, 882236.
2. Fukui Y, Saito M, Nakamura N, Mizuno T, Sato S, Tsukuda M, Nakaoka S, Tsuboi K, Sasaki A, Kuramochi K Boonyaritthongchai , Kaewmanee N, Thirapanmethee K, Chomnawang MT, Bongcheewin B, Nguyen TL, Nguyen HLT, Le HT, Okamoto S, Nakamura T, Nakamura Y, Kubo N. Classification of Southeast Asian mints (Mentha spp.) based on simple sequence repeat markers. Breeding Sci. 2022; 72(2): 181- 187.
3. Khuntayaporn P, Thirapanmethee K, Kanathum P, Chitsombat K, Chomnawang MT. Comparative study of phenotypic-based detection assays for carbapenemase-producing Acinetobacter baumannii with a proposed algorithm in resource-limited settings. PLoS ONE. 2021; 16(11): e0259686.
4. Thirapanmethee K, Kanathum P, Khuntayaporn P, Huayhongthong S, Surassmo S, Chomnawang MT. Cinnamaldehyde: A plant-derived antimicrobial for overcoming multidrug-resistant Acinetobacter baumannii infection. Eur J Integr Med. 2021:101376.
5. Khuntayaporn P, Kanathum P, Houngsaitong J, Montakantikul P, Thirapanmethee K, Chomnawang MT. Predominance of international clone 2 multidrug-resistant Acinetobacter baumannii clinical isolates in Thailand: a nationwide study. Ann Clin Microbiol Antimicrob. 2021;20(1):19.
6. Phacharapiyangkul N, Thirapanmethee K, Sa-ngiamsuntorn K, Panich U, Lee CH, Chomnawang MT. The ethanol extract of Musa sapientum Linn. peel inhibits melanogenesis through Akt signaling pathway. Cosmetics. 2021;8.
7. Thirapanmethee K, Srisiri-A-nun T, Houngsaitong J, Montakantikul P, Khuntayaporn P, Chomnawang MT. Prevalence of OXA-type β-lactamase genes among carbapenem-resistant Acinetobacter baumannii clinical isolates in Thailand. Antibiotics. 2020;9(12):864.
8. Sato R, Sasaki A, Mori Y, Komai M, Kamo S, Onuki M, Seki T, Kawabe Z, Miyajima S, Tomoshige S, Kawasaki T, Sato S, Nakamura T, Kubo N, Takeda S, Date S, Okamoto , Boonyaritthongchai P, Thirapanmethee K, Chomnawang MT, Bongcheewin B, Nguyen TL, Nguyen HLT, Le HT, Nakamura Y, Kuramochi K. Investigation on the Epoxidation of Piperitenone, and Structure–activity Relationships of Piperitenone Oxide for Differentiation-inducing Activity. J Oleo Sci. 2020. https://doi.org/10.5650/jos.ess19278
9. Houngsaitong J, Montakantikul P, Paiboonwong T, Chomnawang MT, Khuntayaporn P, Chulavatnatol S. In vitro activity of biapenem and comparators against multidrug-resistant and carbapenem-resistant Acinetobacter baumannii isolated from tertiary care hospitals in Thailand. Pharm Sci Asia. 2020;47(3):378-386.
10. Homnan N, Thongpraditchote S, Chomnawang M, Thirapanmethee K. In vitro anti-inflammatory effects of Thai herb essential oils. Pharm Sci Asia. 2020;47(2):153-63.
11. Paiboonvong T, Rodjun V, Houngsaitong J, Chomnawang M, Montakantikul P, Chulavatnatol S. Comparative in vitro activity of sitafloxacin against multidrug-resistant and carbapenem-resistant Acinetobacter baumannii clinical isolates in Thailand. Pharm Sci Asia. 2020;47(1):37-42.
12. Huayhongthong S, Khuntayaporn P, Thirapanmethee K, Wanapaisan P, Chomnawang MT. Raman spectroscopic analysis of food-borne microorganisms. 2019; LWT: 114,108419.
13. Khuntayaporn P, Yamprayoonswat W, Yasawong M, Chomnawang MT. Dissemination of carbapenem-resistance among multidrug resistant Pseudomonas aeruginosa Carrying metallo-Beta-lactamase Genes, including the novel blaIMP-65 gene in Thailand. Infect Chemother. 2019; 51(2): 107-18.
14. Phacharapiyangkul N, Thirapanmethee K, Sa-ngiamsuntorn K, Panich U, Lee CH, Chomnawang MT. Effect of Sucrier Banana peel extracts on inhibition of melanogenesis through the ERK signaling pathway. Int J Med Sci. 2019;16(4):602-6.
15. Thongsri P, Sa-Ngiamsuntorn K, Sithisarn P, Chomnawang M. Thirapanmethee, K. Cladogynos orientalis Zipp. extracts inhibit cell culture-derived hepatitis C virus genotype 2a replication in Huh-7 cells through NS5B inhibition. Asian Pac J Trop Biomed. 2019;9(8):346-52.
16. Suwannoi P, Chomnawang M, Tunsirikongkon A, Phongphisutthinan A, Mller-Goymannd CC, Sarisut N. TAT-surface modified acyclovir-loaded albumin nanoparticles as a novel ocular drug delivery system. J Drug Deliv Sci Technol. 2019;52:624-31.
17. Bubpamala J, Khuntayaporn P, Thirapanmethee K, Montakantikul P, Santanirand P, Chomnawang MT. Phenotypic and genotypic characterizations of extended-spectrum beta-lactamase-producing Escherichia coli in Thailand. Infect Drug Resist. 2018;11:2151-7.
18. Tinrat S, Khuntayaporn P, Thirapanmethee K, Chomnawang MT. In vitro assessment of Enterococcus faecalis MTC 1032 as the potential probiotic in food supplements. J Food Sci Technol. 2018;55(7):2384-94.
19. Rattanamaneerusmee A, Thirapanmethee K, Nakamura Y, Bongcheewin B, Chomnawang MT. Chemopreventive and biological activities of Helicteres isora L. fruit extracts. Res Pharm Sci. 2018;13(6):476-83.
20. Rattanamaneerusmee A, Thirapanmethee K, Nakamura Y, Chomnawang MT. Differentiation-inducing effect in human colon cancer cells of essential oils. Pharm Sci Asia. 2018;45(3):154-60.
21. Suwannoi P, Chomnawang M, Sarisuta N, Reichl S, Mller-Goymann CC. Development of Acyclovir-Loaded Albumin Nanoparticles and Improvement of Acyclovir Permeation Across Human Corneal Epithelial T Cells. Journal of Ocular Pharmacology and Therapeutics. 2017;33(10):743-52.
22. Thuengern A, Nathisuwan S, Chomnawang MT, Wiwat C, Thirapanmethee K. Genotypic detection of blaCTX-M1 gene among extended-spectrum beta-lactamases-producing Enterobacteriaceae. J Glob Antimicrob Resist. 2017; 9: 87-93.
23. Phitaktim S, Chomnawang M, Sirichaiwetchakoon K, Dunkhunthod B, Hobbs G, Eumkeb G. Synergism and the mechanism of action of the combination of α-mangostin isolated from Garcinia mangostana L. and oxacillin against an oxacillin-resistant Staphylococcus saprophyticus. BMC Microbiol. 2016; 16: 195.
24. Utchariyakiat I, Surassmo S, Jaturanpinyo M, Khuntayaporn P, Chomnawang MT. Efficacy of cinnamon bark oil and cinnamaldehyde on anti-multidrug resistant Pseudomonas aeruginosa and the synergistic effects in combination with other antimicrobial agents. BMC Compl Altern Med. 2016; 16:158.
25. Wongsariya K, Yasawong M, Bunyapraphatsara N, Chomnawang MT. Development of molecular approach based on PCR assay for detection of histamine producing bacteria. J Food Sci Technol. 2016; 53 (1): 640-8.
