[ Pharmaceutical Sciences Asia - ONLINE ]
E-ISSN 2586-8470
[ Journal Abbreviation: Pharm.Sci.Asia ]
Mahidol University Journal of Pharmaceutical Sciences
  FORMER NAME   "Mahidol University Journal of Pharmaceutical Sciences" Published Since 1974


DOI: 10.29090/psa.2022.01.21.096Pharm Sci Asia 2022; 49(1), 106-113

Pharmacist-led interventions to reduce drug-related problems in prescribing for Vietnamese outpatients

Nhut Anh Nguyen1, Thang Nguyen2*, Suol Thanh Pham2, Thao Huong Nguyen3

1 Department of Pharmacology and Clinical Pharmacy, Nam Can Tho University, Can Tho City, Vietnam
2 Department of Pharmacology and Clinical Pharmacy, Can Tho University of Medicine and Pharmacy, Can Tho City, Vietnam
3 Department of Clinical Pharmacy, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam

Drug-related problems (DRPs) can lead to adverse outcomes and increase the risk of hospitalization. Pharmacist interventions can help to reduce these problems. We aimed to evaluate the effect of pharmacist-led interventions on DRPs in prescribing for outpatients and determine the risk factors of these DRPs. We conducted a before-and-after intervention study on prescribing process for outpatients from a hospital in Vietnam. We collected prescriptions from the hospitals electronic prescription system. Clinical pharmacists determined DRPs following (1) medication leaflets, (2) guidelines of the Vietnam Ministry of Health, (3) Vietnamese National Drug Formulary. We checked drug-drug interactions using Drugs.com. Interventions, including a workshop on DRPs, providing information sheets, and reminding physicians about DRPs, were conducted by researchers in collaboration with clinical pharmacists in the study hospital. In the pre-intervention phase, we analyzed 3352 prescriptions. The number of prescriptions with at least 1 DRP was 88.8%. In the post-intervention, we analyzed 2685 prescriptions. The number of prescriptions with at least 1 DRP decreased from 88.8% to 74.9% (p<0.001). Pharmacist interventions are effective on DRPs in drug indications (p<0.001), dosage (p<0.001), frequency of use (p<0.001), time of taking medications (p<0.001). There was no significant improvement in DRPs of the time of taking drugs compared with meals and drug-drug interaction after interventions. The number of DRP increases with the number of drugs prescribed (p<0.001). In conclusion, pharmacist-led interventions reduced the proportion of prescriptions with DRPs. Prescribing 5 or more medications increased the risk of DRPs occurrence.


Drug-related problems, Outpatients, Prescribing, Pharmacist-led interventions

Download full paper (PDF File size: 1,000.05 KB.)

November-December 2022

See other volume


September-October 2022

See other volume


July-August 2022

See other volume


May-June 2022

See other volume


March-April 2022

See other volume


January-February 2022

See other volume


Aims and Scope
Editorial Board
Publication Ethics
Instruction to Authors
All Volumes & Issues
Submit Online
Contact us
Faculty of Pharmacy Mahidol University
Mahidol University
Member's menu

You're now loging on with following account:
Guest (unknown)

Please Sign in or Register

Pharmaceutical Sciences Asia by Faculty of Pharmacy, Mahidol University, Thailand is licensed under CC BY-NC-ND 4.0

    Copyright © 2017-2024
    Faculty of Pharmacy, Mahidol University, THAILAND

We use Cookies

This site uses cookies to personalise your experience and analyse site traffic. By Clicking ACCEPT or continuing to browse the site you are agreeing to our use of cookies.