[ Pharmaceutical Sciences Asia - ONLINE ]
Print ISSN 2586-8195 E-ISSN 2586-8470
[ Journal Abbreviation: Pharm.Sci.Asia ]
Mahidol University Journal of Pharmaceutical Sciences
  FORMER NAME   "Mahidol University Journal of Pharmaceutical Sciences" Published Since 1974


Pharm Sci Asia ; 29(2),

New leads of HIV-1 Integrase Inhibitors

Opa Vajragupta and Preecha Boonchoong


Following to reverse transcriptase (RT) and protease (PR), integrase (IN) has emerged as an attractive target for new anti-HIV-1 agents. IN was found to be promising candidate because of its necessary for viral life cycle and lack of IN homologous enzymes in the human host. Different classes of HIV-1 IN inhibitors have been reported, for example, aryl 1,3-diketo-containing compounds, hydrazide-containing compounds, styrylquinoline derivatives, L-chicoric acid analogues, thiazolothiazepine derivatives and other hydroxylated compounds including bis-catechols and curcumin. The important structural features that are essential for the inhibition of the integrase are pointed out in this review.


HIV-1 Integrase Inhibitors ,reverse transcriptase , protease ,integrase,anti-HIV-1 agents

September-December 2002

See other volume


January-August 2002

See other volume


Aims and Scope
Editorial Board
Publication Ethics
Instruction to Authors
All Volumes & Issues
Submit Online
Contact us
Faculty of Pharmacy Mahidol University
Mahidol University
Member's menu

You're now loging on with following account:
Guest (unknown)

Please Sign in or Register

    Copyright © 2017
    Faculty of Pharmacy, Mahidol University, THAILAND