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รศ.ดร.ภญ. จิรภรณ์ อังวิทยาธร

รศ.ดร.ภญ. จิรภรณ์ อังวิทยาธร

jiraporn.ung@mahidol.ac.th

jiraporn.ung@mahidol.ac.th
อาจารย์ประจำภาควิชาเภสัชเคมี

ผลงานวิจัยตีพิมพ์

2021

  1. Cyclooxygenase-2 inhibitory activity of chromone compounds by comparative molecular field analysis (Comfa)
    Laosumrit W, Ungwitayatorn J* Chiang Mai Journal of Science 2021; 48(4): 1045-1056.


2020

  1. Molecular docking study of chromone derivatives as dual inhibitor against plasmepsin II and falcipain-2
    Maicheen C, Ungwitayatorn J*. Chiang mai journal of science 2020; 47(1); 98-113.


2019

  1. Antimalarial and beta-hematin formation inhibitory activities of chromone derivatives
    Maicheen C, Ungwitayatorn J*. ScienceAsia 2019; 45(3); 221-228.


2018

  1. Topoisomerase I inhibitory activity and 3D QSAR studies of chromone derivatives.
    Maicheen C, Phosrithong N, Jittikoon J, Ungwitayatorn J.* Chiang Mai Journal of Science 2018; 45(2): 1073-1086


2017

  1. Biological activity evaluation and molecular docking study of chromone derivatives as cyclooxygenase-2 inhibitors
    Maicheen C, Phosrithong N, Ungwitayatorn J*. Medicinal Chemistry Research 2017; 26(3): 662-671

  2. Molecular docking study of phthalimide derivatives as non-nucleoside HIV-1 reverse transcriptase inhibitor.
    Maicheen C, Samee W, Ungwitayatorn J.* Chiang Mai J Sci 2017; 44(4): 1395-406.


2016

  1. 3D-QSAR studies on lipid peroxidation inhibitory activity of chromone derivatives
    Phosrithong N, Ungwitayatorn J*. Medicinal Chemistry Research 2016; 25(10): 2368-2379.


2014

  1. 3D-QSAR studies of chromone derivatives as iron-chelating agent
    Phosrithong N, Ungwitayatorn J*. Medicinal Chemistry Research 2014; 23(2): 1037-1045

  2. Antimalarial activity of HIV-1 protease inhibitor in chromone series
    Lerdsirisuk P, Maicheen C, Ungwitayatorn J*. Bioorganic Chemistry 2014; 57: 142-147

  3. Molecular docking studies of chromone derivatives against wild type and mutant strains of HIV-1 protease
    Nunthanavanit P, Ungwitayatorn J*. Medicinal Chemistry Research 2014; 23(9): 4198-4208


2013

  1. Docking study on anticancer activity of chromone derivatives
    Maicheen C, Phosrithong N, Ungwitayatorn J*. Medicinal Chemistry Research 2013; 22(1): 45-56

  2. Ligand-based CoMFA and CoMSIA studies on chromone derivatives as radical scavengers
    Phosrithonga N, Ungwitayatorn J*. Bioorganic Chemistry 2013; 49(2013): 9-15

  3. QSAR Analysis of Chromone Derivatives as HIV-1 Protease Inhibitors
    Sameea W, Ungwitayatorn J* Mahidol University Journal of Pharmaceutical Sciences 2013; 40 (3), 8-15

  4. Synthesis, Topoisomerase I Inhibitory and Cytotoxic Activities of Chromone Derivatives
    Maicheen C, Jittikoon J, Vajragupta O, Ungwitayatorn J*. Medicinal Chemistry 2013; 9(3): 329-339


2012

  1. 3D-QSAR studies of natural flavonoid compounds as reverse transcriptase inhibitors
    Phosrithong N, Samee W, Ungwitayatorn J*. Med Chem Res 2012; 21(5): 559-567

  2. In Vitro Antioxidant Activity Study of Novel Chromone Derivatives
    Phosrithong N, Samee W, Nunthanavanit P, Ungwitayatorn J*. Chemical Biology and Drug Design 2012; 79(6): 981-989


2011

  1. Synthesis, in vitro evaluation, and docking studies of novel chromone derivatives as HIV-1 protease inhibitor
    Ungwitayatorn J*, Wiwat C, Samee W, Nunthanavanit P, Phosrithong N. Journal of Molecular Structure 2011; 1001(1 มี.ค.): 152-161


2010

  1. Molecular docking study on anticancer activity of plant-derived natural products
    Phosrithong N, Ungwitayatorn J*. Med Chem Res 2010; 19(8): 817-835.


2008

  1. 3D-QSAR investigation of synthetic antioxidant chromone derivatives by molecular field analysis
    Samee W, Nunthanavanit P, Ungwitayatorn J Int J Mol Sci. 2008; 9(3): 235-246

  2. 3D-QSAR studies on chromone derivatives as HIV-1 protease inhibitors: application of molecular field analysis
    Nunthanavanit P, Anthony NG, Johnson BF, Mackay SP, Ungwitayatorn J Arch Pharm. 2008; 341(6): 357-364

  3. Synthesis and HIV-1 reverse transcriptase inhibitory activity of non-nucleoside phthalimide derivatives.
    Ungwitayatorn J*, Wiwat C, Matayatsuk C, Pimthon J, Piyaviriyakul S. Chinese J Chem 2008; 26(2): 379-387. Feb


2004

  1. 3D-QSAR studies on chromone derivatives as HIV-1 protease inhibitors,
    Ungwitayatorn J*, Samee W, Pimthon J. J Mol Struct 2004; 689 (1-2):99-106.

  2. 3D-QSAR Studies on Phthalimide Derivatives as HIV-1 Reverse Transcriptase Inhibitors.
    Samee W, Ungwitayatorn J, Matayatsuk C, and Pimthon J ScienceAsia 2004; 30:81-88.

  3. Radical Scavenging Activity Relationships of the Synthesized Chromone Derivatives.
    Samee W, Sae-Lee N, Ungwitayatorn J, Srinakharinwirot J Pharm Sci 2004; 9(1), 36-42


2003

  1. 3D-QSAR Studies on Phthalimide Derivatives as HIV-1 Reverse Transcriptase Inhibitors
    Ungwitayatorn J, Samee W, Matayatsuk C, Pimthon J Proceedings in The Seventh Annual Symposium on Computational Science and Engineering, 24-26 March 2003, Bangkok page 224-235

  2. Active Site Binding Modes of HIV-1 Reverse Transcriptase Inhibitors from Natural Products.
    Samee W, Ungwitayatorn J. Srinakharinwirot J Pharm Sci 2003;8(1), 10-24.


2002

  1. Docking Study of Chromone Derivatives as HIV-1 Protease Inhibitors
    Ungwitayatorn J,Samee W Mahidol J Pharm Sci 2002; 29(3-4)


2001

  1. Quantitative structure-activity relationship study on phthalimide derivatives as HIV-1 reverse transcriptase inhibitors.
    Ungwitayatorn J, Matayatsuk C, and Sothipatcharasai P. ScienceAsia 2001; 27:245-250.

  2. Synthesis and evaluation of Phthalimide and benzofuran derivatives as potential HIV-1 Reverse Transcriptase Inhibitors.
    Ungwitayatorn J, Chanpen W, Matayasuk C, Sripha K, Kamalanonth P. Songklanakarin J Sci Technol 2001; 23(2): 235-245


2000

  1. Docking study on phthalimide derivatives: HIV-1 reverse transcriptase inhibitors.
    Ungwitayatorn J, Sothipatcharasai P. Srinakharinwirot J Pharm Sci 2000; 5(1): 19-27

  2. Synthesis and evaluation of chromone derivatives as potential HIV-1 protease inhibitors.
    Ungwitayatorn J, Wiwat C, Samee W Thai J Pharm Sci 2000; 24(3-4): 155-164


1999

  1. Comparative molecular field analysis (CoMFA) of the phthalimido derivatives as potential HIV-1 reverse transcriptase inhibitors.
    Ungwitayatorn J, Amornlervit P, Sothipatcharasai P. Proceedings in the Third Annual Symposium on Computational Science and Engineering, March 20-24, 1999, Faculty of Science, Chulalongkorn University, Bangkok, Thailand. 1999; 206-215


1997

  1. 3-Dimensional quantitative structure activity relationship (3-D QSAR): Comparative molecular field analysis (CoMFA).
    Ungwitayatorn J Proceedings of the First Indochina Conference on Pharmaceutical Sciences (Pharma.... 1997; 413-418

  2. Quantitative structure-activity relationship (QSAR) study of polyhydroxyxanthones.
    Ungwitayatorn J, Pickert M, Frahm AW. Pharm Acta Helv 1997; 72: 23-9


1993

  1. Design and synthesis of bicyclic non-peptide ß-bend mimetic of enkephalin.
    Currie BL, Krestenasky JL, Lin Z, Ungwitayatorn J, Lee Y-H, del Roxario-Chow M, Sheu W, Johnson ME. Tetrahedron 1993;49:3489-500


1991

  1. Manganic acetate mediated transformation of enol-ethers into gamma-lactones.
    del Rosario-Chow M, Ungwitayatorn J, Currie BL. Tetrahedron Letters 1991; 32: 1011-1014


1982

  1. Thai Crude Drugs; Their Preparations and Specification: No. 13
    Sappkun N, Ungwitayatorn J. Mahidol University J Pharm Sci 1982; 9(3): 53-58



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