[ Pharmaceutical Sciences Asia - ONLINE ]
E-ISSN 2586-8470
[ Journal Abbreviation: Pharm.Sci.Asia ]
Mahidol University Journal of Pharmaceutical Sciences
  FORMER NAME   "Mahidol University Journal of Pharmaceutical Sciences" Published Since 1974


DOI: https://doi.org/10.29090/psa.2018.01.013Pharm Sci Asia 2018; 45(1), 13-21

Investigation on medication use and factors associated with levels of asthma control among asthmatic outpatients at University Medical Center Hochiminh City

D.T.V. Duy, D.N.D. Trang

1 Department of Clinical Pharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy, Hochiminh City, Vietnam
2 Department of Pharmacy, University Medical Center Hochiminh City, University of Medicine and Pharmacy, Hochiminh City, Vietnam

Asthma is a common chronic disease that affects millions of people of all ages. Despite the availability of evidence – based management guidelines focusing on asthma control, recent data showed that control of asthma was suboptimal worldwide. The assessment of asthma control and associated factors is thus very necessary in the management of asthma in both community and clinical settings. A descriptive cross-sectional study on 308 asthmatic outpatients aged 12 years old and over was conducted at University Medical Center Hochiminh City (HCMC). Asthma severity was classified by EPR-3 guideline. The level of asthma control was assessed by the Vietnamese version of ACT and factors associated with asthma control were evaluated by medical history, patients and disease characteristics. The mean age of study population was 45.47 ± 16.99 and 69.8% were female. The top three medications prescribed were inhaled corticosteroid (ICS), long – acting β2 agonist, leukotriene receptor antagonist. The mean ACT score was 20.41 ± 3.96; 59.1% of the study population was found to be well-controlled (ACT ≥ 20) and 40.9% was categorized as uncontrolled (ACT < 20). Education, asthma severity, step – up therapy, frequency of preventive medication use were found to be significantly associated with the level of asthma control. The high proportion of uncontrolled asthma suggested the need for strategies to enhance effectiveness of asthma control in University Medical Center HCMC in particular and in Vietnam in general. Further studies should be conducted on larger sample to determine the association between asthma control and comorbidities as well as ICS dosage


asthma control, ACT, outpatients, inhaled corticosteroid

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