[ Pharmaceutical Sciences Asia - ONLINE ]
Print ISSN 2586-8195 E-ISSN 2586-8470
[ Journal Abbreviation: Pharm.Sci.Asia ]
Mahidol University Journal of Pharmaceutical Sciences
  FORMER NAME   "Mahidol University Journal of Pharmaceutical Sciences" Published Since 1974

 
Abstracts

Pharm Sci Asia ; 39(3),
 

3D QSAR and Pharmacophore Identification Studies of Some Factor VIIa Inhibitors

P. Choudhari*, M. Bhatia, S. Jadhav

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3D QSAR and pharmacophore identification studies plays vital role in development of new potent NCE’s. Various Coagulation factors are emerging target for the anticoagulant drug design. Here we report 3D QSAR and pharmacophore identification studies on 50 reported factor VIIa inhibitors. The QSAR equation and pharmacophore identification yielded that the presence of electron with drawing groups are important for factor VIIa inhibition.


Keyword:

3D QSAR, Pharmacophore, Factor VIIa, Vlife MDS 3.5




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Vol.39
No.3-4
July - December 2012

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Vol.39
No.2
April - June 2012

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Vol.39
No.1
January - March 2012

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