[ Pharmaceutical Sciences Asia - ONLINE ]
E-ISSN 2586-8470
[ Journal Abbreviation: Pharm.Sci.Asia ]
Mahidol University Journal of Pharmaceutical Sciences
  FORMER NAME   "Mahidol University Journal of Pharmaceutical Sciences" Published Since 1974


Pharm Sci Asia ; 34(1),

Antimicrobial Activity of Essential Oils Against Five Strains of Propionibacterium acnes

S. Luangnarumitchai, S. Lamlertthon,* and W. Tiyaboonchai


The present study was conducted to evaluate the in vitro antibacterial activities of 22 essential oils from Thai medicinal plants against 5 strains of Propionibacterium acnes (P. acnes). Antibacterial activity of essential oils was investigated using disc diffusion and agar dilution methods. The results showed that 19 oils could inhibit the growth of P. acnes. According to the inhibition zone, kaffir lime leaf (Citrus hystrix DC.), lemongrass oil (Cymbopogon citratus (DC.) Stapf), clove oil (Syzygium aromaticum (L.) Merr. & Perry) and michelia oil (Michelia alba DC.) had the strongest antibacterial activity. The results form the agar dilution method showed the same trend in which lemongrass oil and citronella oil showed the lowest minimum inhibitory concentration against 5 strains bacteria at 0.125% v/v. Therefore, these two essential oils are an interesting source for further study and possibly as an alternative acne treatment.


acne vulgaris, antibacterial activity, essential oils, Propionibacterium acnes, Antimicrobial, lemongrass oil, citronella oil

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