[ Pharmaceutical Sciences Asia - ONLINE ]
Print ISSN 2586-8195 E-ISSN 2586-8470
[ Journal Abbreviation: Pharm.Sci.Asia ]
Mahidol University Journal of Pharmaceutical Sciences
  FORMER NAME   "Mahidol University Journal of Pharmaceutical Sciences" Published Since 1974


DOI: https://doi.org/10.14456/mujps.2016.16Pharm Sci Asia 2016; 43(3), 135-142

Setting priorities for introducing new vaccines into the national immunization program; a systematic review

S. Pooripussarakul, A. Riewpaiboon*

- Division of Social and Administrative Pharmacy, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand

This study aimed to review criteria to support decision-making on national immunization programs. A systematic review was conducted for publication during 2000-February 2016 from three major databases including PubMed, the Cochrane Library, and Scopus. Manual search from cited references and websites were also used. Inclusion criteria were theoretical concepts of new vaccine introduction and decision making tool of vaccine introduction. Exclusion criteria were clinical guideline of specific vaccines or diseases, research on vaccine development or laboratory test, proceedings, and articles not in English. Five articles were found. The criteria for a decision-making for new vaccine introduction included technical criteria, programmatic and operational criteria, and qualitative criteria. Technical criteria included epidemiology, vaccine effectiveness and safety, and economic evaluations. Programmatic and operational criteria included vaccine availability, feasibility to incorporate into the existing program, and logistics. Public health criteria e.g. public acceptance, equity, politic, policy was also considered. Although the criteria of a vaccine introduction seem similar among articles but the frameworks were different in details and weighted factors due to specific context. These analytical frameworks were useful in decision-making process but did not allow prioritization of new vaccines at the same time. However the basic criteria and evaluation methods could be applied to fit local setting in individual country.


priority, vaccine, Immunization

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