[ Pharmaceutical Sciences Asia - ONLINE ]
Print ISSN 2586-8195 E-ISSN 2586-8470
[ Journal Abbreviation: Pharm.Sci.Asia ]
Mahidol University Journal of Pharmaceutical Sciences
  FORMER NAME   "Mahidol University Journal of Pharmaceutical Sciences" Published Since 1974


Pharm Sci Asia ; 32(2),

Factors Affecting Sizes of Magnetic Particles

N. Tresilwised, P. Pithayanukul* and C. Plank


Magnetic particles are used for medical and pharmaceutical purposes such as delivery systems for drugs, genes, and radionuclides. In this study, the technique of chemical co-precipitation in aqueous solution was applied for the synthesis of iron-based magnetic particles. The size and size distribution of magnetic particles were determined by photon correlation spectroscopy. Oxygen-free conditions achieved by vacuum or nitrogen gas bubbling during the process of synthesis, together with the addition of an appropriate coating material (citric acid or linear polyethyleneimine) resulted in a stable dispersion of the magnetic colloid with average hydrodynamic diameter of 217-329 nm and polydispersity index of particle size distribution of 0.13-0.28


chemical co-precipitation, magnetic particles, particle sizes, Oxygen-free condition

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