[ Pharmaceutical Sciences Asia - ONLINE ]
E-ISSN 2586-8470
[ Journal Abbreviation: Pharm.Sci.Asia ]
Mahidol University Journal of Pharmaceutical Sciences
  FORMER NAME   "Mahidol University Journal of Pharmaceutical Sciences" Published Since 1974

 
Abstracts

DOI: 10.29090/psa.2024.03.24.AP0672Pharm Sci Asia 2024; 51(3), 204-213
 

Assessing Quality of Life Using Zhan's Concept Among Thai Osteoarthritis Patients: A Structural Equation Modelling Approach

Patcharee Duangchan1, Somying Pumtong2,*, Nattaporn Yoopan3

1 Department of Social Pharmacy, Faculty of Pharmacy, Srinakharinwirot University, Nakhonayok, Thailand
2 Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand
3 Department of Biopharmacy, Faculty of Pharmacy, Srinakharinwirot University, Nakhonayok, Thailand


Quality of life (QoL) in Thai patients with knee osteoarthritis and its predicting factors according to Zhan’s concept have been well described by various studies; but not all predicting factors have been simultaneously tested in a single study. This study aimed to examine quality of life of Thai patients with knee osteoarthritis, as well as direct effects of personal factors, health-related factors, and social/culture/environmental factors on quality of life of patients with knee osteoarthritis. 300 patients aged 60 years or older receiving care at five hospitals in Nakhonnayok, Thailand, were purposively selected from May 2019 to June 2020. Participants completed the knee osteoarthritis severity scale, social support scale, quality of life scale, and demographic and health status questions. Structural equation modeling was used to analyze the data. Overall quality of life was at a moderate level. Knee osteoarthritis severity; which was a health-related factor, and social support; which was social/culture/environmental factors, had significantly, negative and positive direct effects on quality of life, respectively. These two causal factors could explain 33% of the variance of quality of life. Healthcare providers and settings should provide more programs with activities to promote social support and alleviate knee osteoarthritis severity for the Thai elderly patients with knee osteoarthritis.


Keyword:

Quality of life, Knee osteoarthritis, Thai patients, Structural equation modeling




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